Chronic Cutaneous Lupus Erythematosus
Well-defined, erythematous plaque
with scaling and prominent follicular plugging on the nose.
A 45 year old woman had a history of Systemic Lupus Erythematosus
onset at the age of 34 with Raynaud's phenomenon, arthralgia,
arthritis, fever and malar rash. She had high
antinuclear autoantibody titers on HEp-2 cells, nRNP, Sm, and
anticardiolipin IgG antibodies.
The malar dermatitis evolved to a
CCLE plaque with prominent scaling. Further discoid lesions appeared
on the scalp, ears,
trunk, upper extremities and hands, on both dorsal
and palmar surface despite topical
steroids, antimalarials and prednisone therapy.
Various SLE manifestations may show a different
response to therapy: the steroid doses used to control this patient's
arthritis did not improve the skin lesions.
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"On-line Archives of Rheumatology",