This 18 year old SLE patient came to our Department due to a recent onset (3 months earlier) of malar rash and constitutional symptoms (weakness and malaise). The patient reported having a 5-year history of Raynaud's phenomenon and arthralgia.
Abnormal results of laboratory studies included the presence of ANA, anti-nDNA, anti-SS-A autoantibodies and a proteinuria of approximately 10 g/d.
Renal biopsy revealed a Class IV lupus glomerulonephritis and therefore a course of high-dose oral corticosteroids and cyclophosphamide was prescribed.
The rash responded well to the treatment.