Anti-phospholipid Antibody Syndrome
Erythematous macules on the face.
This 24 year old woman developed a catastrophic antiphospholipid syndrome.
The onset was abrupt, with bilateral adrenal infarction and resulting
Addison's disease, right kidney infarction, and deep vein thrombosis of the
left leg with pulmonary embolism.
Laboratory examinations revealed immunohemolytic anemia and
thrombocytopenia (Evans' syndrome).
Moreover, she had high titres of anticardiolipin antibodies of IgG and IgM
class and lupus anticoagulant.
At the time of her admission to our Department she had areas of
cutaneous necrosis on the hears and erythematous macules on the face.
The pathological examination of a biopsy from a plaque on the face showed
microthrombosis in the dermal vessels without vasculitis.
All contents copyright of the "On-line Archives of Rheumatology", 1996