Subacute Cutaneous Lupus Erythematosus

Papulosquamous (psoriasiform) SCLE rash.


Clinical Background:

IMAGE This patient was admitted to our Department for the first time at the age of 47. She had been suffering from "photosensitive rashes" for at least 3 years without overt constitutional or systemic symptoms, and had undergone different topical treatments with partial and temporary benefits.
Physical examination showed extensive butterfly eruption and a papulosquamous SCLE rash involving the neck, upper trunk, extensor surfaces of the arms and hands.
Laboratory investigations revealed the presence of leukopenia and high antinuclear, anti-SS-A, anti-SS-B and IgG anticardiolipin autoantibody titres. No clinical evidence of sicca syndrome was found.
She was administered hydroxychloroquine (200 mg/d) and prednisone (25 mg/d) with prompt remission of the leukopenia. The rash improved but did not resolve completely during a two-year follow-up period.

All contents copyright of the "On-line Archives of Rheumatology", 1996