Cutaneous or systemic vasculitis may be observed in myelodysplasia as well as in lymphoproliferative and myeloproliferative disease.
A study of 162 patients with myelodysplasia reported 13 cases of vasculitis (8%) in which the cutaneous vasculitis was often the first clinical manifestation of myelodysplasia.
Furthermore, few cases of panniculitis due to vasculitic involvement of the subcutaneous vessels have been described.
Vasculitic manifestations generally respond well to systemic steroid treatment.