Localized Scleroderma
Unusual association between Plaque Morphea and Erythema Annulare
Centrifugum
Clinical Background:
A 43 year old male patient reported having a sclerodermic
plaque in the lumbar area
for approximately one year. In the same period some
annular erythematous areas on the
thighs and buttocks were noted.
The latter extended to form large circular shapes, continuously modified by the regression
of some areas and the appearance of new plaques merging together to form wide polycyclic
patterns.
Several cultural examinations previously performed by the patient's G.P. did not allow to
isolate dermatophytes or other pathogens.
Furthermore, local antimycotic treatment had not altered the clinical evolution of the
rash.
Physical examination revealed a wide morphea plaque in the left lumbar region with
characteristically thickened, taut skin with an ivory white smooth surface, surrounded by
a lilac ring.
Annular erythematous lesions, some of which forming incomplete rings, slightly raised with
fine scaling, were present on the thighs and buttocks (superficial gyrate erythema).
Laboratory investigations, radiological and echotomographical exams did not disclose any
signs of infectious, parasitic, neoplastic or other systemic disease.
He was started on griseofulvin (500 mg/d) with prompt resolution of the gyrate erythema.
Six months later the morphea plaque was stationary.
Comment:
The association of morphea and gyrate erythema is probably
incidental rather than
being the expression of a common pathogenetic
substrate.
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